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Renal changes after an uncomplicated antireflux operation
The Journal of Urology
|June 1, 1976
Summary
Successful ureteral reimplantation did not resolve persistent defects in most patients with prior pyelographic changes. Renal size differences remained static, suggesting renal dysgenesis may be a key factor alongside reflux.
Area of Science:
- Pediatric Urology
- Nephrology
Background:
- Ureteral reimplantation is a common surgical procedure for treating vesicoureteral reflux (VUR).
- Preoperative pyelographic changes in children with VUR may indicate underlying renal damage.
Purpose of the Study:
- To investigate the persistence of renal defects after successful ureteral reimplantation in patients with preoperative pyelographic changes.
- To assess the impact of successful VUR treatment on renal size discrepancies.
Main Methods:
- Retrospective analysis of patients who underwent ureteral reimplantation for VUR.
- Evaluation of preoperative and postoperative pyelograms to assess renal morphology.
- Comparison of renal size ratios between affected and unaffected kidneys.
Main Results:
- Persistent defects were observed in 91% of patients with preoperative pyelographic changes post-reimplantation.
- Renal size ratios remained static, even after infection eradication.
- Successful VUR treatment did not significantly alter established renal size differences.
Conclusions:
- Successful ureteral reimplantation may not reverse all structural renal abnormalities associated with VUR.
- Renal dysgenesis is hypothesized as a significant contributing factor to persistent defects and static renal size ratios.
- Further investigation into the role of renal dysgenesis in VUR outcomes is warranted.