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Related Experiment Videos

Trifocal uveal melanoma

N Lois1, C L Shields, J A Shields

  • 1Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

American Journal of Ophthalmology
|December 24, 1997
PubMed
Summary
This summary is machine-generated.

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This case report details a rare instance of a patient developing three separate uveal melanomas over three decades. Early recognition of multifocal uveal melanoma is crucial.

Area of Science:

  • Ophthalmology
  • Oncology

Background:

  • Uveal melanoma is the most common primary intraocular malignancy.
  • Multifocal and bilateral presentations are exceedingly rare.

Observation:

  • A 50-year-old male patient presented with a history of three noncontiguous uveal melanomas diagnosed over a 30-year period.
  • The patient had an iris melanoma and bilateral choroidal melanomas.

Findings:

  • Systemic evaluation revealed no evidence of metastases or other primary neoplastic disease.
  • The patient's condition highlights a unique presentation of uveal melanoma.

Implications:

  • Clinicians should consider the possibility of multifocal and bilateral uveal melanoma, even in the absence of systemic disease.

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  • This case underscores the importance of long-term surveillance in patients with uveal melanoma.