Genetic disorders in house mouse germ cells after the Chernobyl catastrophe
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Updated: Oct 31, 2026

Transgenic Rodent Assay for Quantifying Male Germ Cell Mutant Frequency
Published on: August 6, 2014
M D Pomerantseva1, L K Ramaiya, A V Chekhovich
1N.I. Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Abstract:
Genetic effects were studied in house mice caught from 1986 to 1994 in regions polluted by radionuclides as a result of the Chernobyl disaster. The dose rates of gamma-radiation on the soil surface ranged from 0.0002 to 2 mGy/h. The frequency of reciprocal translocations in mouse spermatocytes was relatively low, but increased with the dose rate. Embryo mortality was increased only in the progeny of male mice in males caught in 1987 in the area with maximal contamination. The frequency of mice heterozygous for recessive lethal mutations decreased with time after the accident.
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