Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cinemakeratography using computer morphing

M K Smolek1, S D Klyce

  • 1Lions Eye Research Laboratories, LSU Eye Center, Louisiana State University Medical Center, New Orleans, USA. msmole@lsumc.edu

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|December 24, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Developments in corneal topographic analysis following contact lens wear and refractive surgery.

Contact lens & anterior eye : the journal of the British Contact Lens Association·2005
Same author

Contribution of the ocular surface to visual optics.

Experimental eye research·2004
Same author

Screening of prior refractive surgery by a wavelet-based neural network.

Journal of cataract and refractive surgery·2001
Same author

Effect of larger ablation zone and transition zone on corneal optical aberrations after photorefractive keratectomy.

Archives of ophthalmology (Chicago, Ill. : 1960)·2001
Same author

Gender- and age-related differences in corneal topography.

Cornea·2001
Same author

Corneal topography and the new wave.

Cornea·2000

Computer animation of corneal topography revealed dynamic changes in keratoconus and after photorefractive keratectomy (PRK). This visualization technique, Cinema-K, aids in understanding subtle corneal shape alterations over time.

Area of Science:

  • Ophthalmology
  • Biomedical Engineering

Background:

  • Corneal topography analysis is crucial for diagnosing and monitoring conditions like keratoconus and assessing outcomes after refractive surgery.
  • Traditional videokeratography provides static snapshots, limiting the visualization of dynamic corneal shape changes over time.

Purpose of the Study:

  • To animate TMS-1 videokeratography data using computer morphing to visualize dynamic corneal shape changes.
  • To enhance the understanding of subtle topographical alterations in keratoconus and post-photorefractive keratectomy (PRK) corneas over extended periods.

Main Methods:

  • Computer morphing techniques were applied to serial videokeratography data from patients with keratoconus (8 examinations over 76 months) and post-PRK corneas (8 examinations over 37 months).
  • The Keratoconus Prediction Index (KPI) and Surface Regularity Index (SRI) were analyzed in conjunction with the animated topography.

Related Experiment Videos

Main Results:

  • Keratoconus animation showed progressive inferior cone steepening, periodic superior flattening/steepening, and eventual cone regression, with a non-drifting apex.
  • The KPI demonstrated a plateau and subsequent drop in the keratoconus group.
  • Post-PRK animation revealed continuous corneal remodeling up to 30 months, with fluctuating ablation zones correlating with SRI changes.

Conclusions:

  • Cinemakeratography (Cinema-K) effectively visualizes dynamic corneal changes, improving the appreciation of subtle topographical alterations.
  • This animation technique offers a valuable tool for clinical assessment and research in corneal ectasias and refractive surgery outcomes.