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Related Experiment Videos

Pulsus alternans in diastolic left ventricular dysfunction--a case report

T Kwan1, A Feit, M Alam

  • 1Department of Medicine, State University of New York, Health Science Center, Brooklyn 11203, USA.

Angiology
|December 24, 1997
PubMed
Summary
This summary is machine-generated.

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Pulsus alternans, typically linked to systolic dysfunction, was observed in a patient with diastolic dysfunction and normal systolic function. Successful renal artery revascularization resolved this pulsus alternans.

Area of Science:

  • Cardiology
  • Nephrology
  • Pulmonary Hypertension

Background:

  • Pulsus alternans is commonly associated with severe left ventricular systolic dysfunction.
  • Diastolic dysfunction, characterized by impaired ventricular relaxation and filling, can also lead to significant hemodynamic alterations.

Observation:

  • A case study involving a patient presenting with recurrent pulmonary edema and severe hypertension.
  • The patient exhibited bilateral renal artery stenosis but maintained normal systolic ventricular function.
  • Pulsus alternans was detected in pulmonary artery, right ventricle, and left ventricle pressure tracings.

Findings:

  • Pulsus alternans was present despite preserved systolic function, suggesting an alternative etiology.
  • The pulsus alternans resolved completely following successful renal artery revascularization.

Related Experiment Videos

  • This indicates a potential link between renal artery stenosis, diastolic dysfunction, and pulsus alternans.

    • Implications:

    • Pulsus alternans may occur in the setting of isolated diastolic dysfunction, challenging traditional diagnostic assumptions.
    • Renal artery stenosis should be considered in patients with unexplained pulsus alternans, particularly those with hypertension and signs of fluid overload.
    • Successful revascularization can reverse pulsus alternans, highlighting the importance of identifying and treating renovascular hypertension.