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The mechanism of Golgi segregation during mitosis is cell type-specific
H Stanley1, J Botas, V Malhotra
1Biology Department, University of California at San Diego, La Jolla, CA 92093-0347, USA.
Abstract:
Golgi membranes in Drosophila embryos and tissue culture cells are found as discrete units dispersed in the cytoplasm. We provide evidence that Golgi membranes do not undergo any dramatic change in their organization during the rapid mitotic divisions of the nuclei in the syncitial embryo or during cell division postcellularization. By contrast, in Drosophila tissue culture cells, the Golgi membranes undergo complete fragmentation during mitosis. Our studies show that the mechanism of Golgi partitioning during cell division is cell type-specific.