Related Experiment Videos
Interstitial cystitis and bladder mastocytosis in a woman with chronic urticaria
G R Sant1, T C Theoharides, R Letourneau
1Department of Urology, Tufts University School of Medicine, New England Medical Center Hospitals, Boston, MA 02111, USA.
Scandinavian Journal of Urology and Nephrology
|December 24, 1997
Abstract:
A patient with chronic urticaria and angioedema developed endoscopically confirmed interstitial cystitis. Bladder biopsy revealed bladder mastocytosis with > 60 mast cells/mm2 (normal < 10) in the detrusor and submucosa. Most of the mast cells were activated and degranulated. The occurrence of IC in a patient with urticaria and angioedema, diseases both associated with mast cell pathophysiology, supports the role of mast cells in interstitial cystitis.