Essential hypertension and abnormal upper airway resistance during sleep
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Updated: Sep 9, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
1Department of Nephrology, Tel Aviv Medical Center, Israel.
Abstract:
The epidemiological, clinical, hereditary, biochemical, hematological, and physiological characteristics of essential hypertension (EH) and obstructive sleep apnea (OSA) are reviewed here. This extensive review shows that essential hypertension and sleep-disordered breathing--independently of whether it is OSA syndrome or upper airway resistance syndrome--share strikingly similar characteristics. The accumulated data obtained by many different researchers support the hypothesis that EH is mainly due to increased upper airway resistance during sleep. If this hypothesis is correct, treating disorders that cause increased upper airway resistance, particularly during sleep, would be an important part of the treatment of essential hypertension.
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