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Opioids: overview on action, interaction and toxicity

K A Lehmann1

  • 1Department of Anaesthesiology, University of Cologne, Germany.

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
|December 24, 1997
PubMed
Summary
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This review covers the history and current uses of opioid medications, including their effectiveness, side effects, and administration methods. It also addresses physician concerns regarding opioid dependence and addiction.

Area of Science:

  • Pharmacology
  • Medical History

Background:

  • Opioid medications have a long history of use in pain management.
  • Understanding their appropriate application is crucial for effective patient care.

Purpose of the Study:

  • To review the historical context of opioid use.
  • To discuss current accepted indications for opioid prescriptions.
  • To address physician concerns regarding opioid dependence and addiction.

Main Methods:

  • Literature review of historical and current opioid use.
  • Discussion of clinical aspects including dosage, administration, efficacy, and side effects.

Main Results:

  • Accepted indications for opioid use are detailed.

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  • Information on dosage, administration, efficacy, duration, and onset of effect is provided.
  • Potential side effects and physician concerns about dependence and addiction are examined.
  • Conclusions:

    • Current guidelines and understanding of opioid use are presented.
    • The review aims to inform physicians on the safe and effective use of opioids.
    • Addressing physician concerns is key to responsible opioid prescribing practices.