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Heat inactivation of Mycobacterium paratuberculosis in raw milk: are current pasteurization conditions effective?

J R Stabel1, E M Steadham, C A Bolin

  • 1National Animal Disease Center, U.S. Department of Agriculture, Ames, Iowa 50010, USA. jstabel@nadc.ars.usda.gov

Insights

Commercial pasteurization may not eliminate Mycobacterium paratuberculosis in raw milk. However, laboratory tests show that a 15-second treatment at 72°C effectively kills this bacteria in milk.

Area of Science:

  • Food safety science
  • Microbiology
  • Veterinary public health

Background:

  • Mycobacterium paratuberculosis (MAP) is a pathogen found in raw milk.
  • The efficacy of commercial pasteurization against MAP is not well-established.
  • MAP is linked to Johne's disease in cattle and potentially Crohn's disease in humans.

Purpose of the Study:

  • To determine if standard commercial pasteurization effectively eliminates Mycobacterium paratuberculosis from raw milk.
  • To evaluate the impact of different temperatures and holding times on MAP survival.
  • To assess the effectiveness of a specific laboratory-scale pasteurization process.

Main Methods:

  • Holder pasteurization tests were conducted using contaminated raw milk at temperatures ranging from 65°C to 76°C for 0 to 30 minutes.
  • A laboratory-scale pasteurizer was used to treat raw milk with Mycobacterium paratuberculosis.
  • Bacterial viability was assessed after each treatment condition.

Main Results:

  • Residual populations of viable Mycobacterium paratuberculosis were detected after holder pasteurization treatments at various temperatures and durations.
  • Laboratory-scale pasteurization at 72°C for 15 seconds demonstrated complete inactivation of Mycobacterium paratuberculosis.
  • This suggests that specific pasteurization parameters are crucial for effective bacterial kill.

Conclusions:

  • Standard holder pasteurization may not be sufficient to eliminate Mycobacterium paratuberculosis from raw milk.
  • Optimized pasteurization parameters, such as 72°C for 15 seconds, are effective in killing Mycobacterium paratuberculosis.
  • Further research into commercial pasteurization efficacy against MAP is warranted to ensure milk safety.

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