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Cardiorespiratory response to exercise in patients with exercise-induced bronchial obstruction
R Baba1, M Nagashima, N Tauchi
1Department of Pediatrics, Nagoya University School of Medicine, Japan.
Objective:
To document the characteristics of the ventilatory response to exercise in patients with exercise-induced bronchial obstruction (EIB).
Experimental Design:
Comparative study during the period between December 1993 and March 1994.
Setting:
Ambulatory care in Ohgaki Municipal Hospital.
Subjects And Method:
We evaluated 11 children with EIB. Each subject under went symptom-limited cardiopulmonary treadmill exercise testing (Bruce protocol).
Results:
Patients with EIB showed a significantly lower peak oxygen consumption (peak VO2) than the control subjects. Three patients with EIB developed relative hypoventilation during incremental exercise: an increase in end-tidal carbon dioxide partial pressure (PETCO2) and a decrease in VE/VCO2 were observed at the end-stage of exercise testing.
Conclusions:
These findings demonstrate that some patients with EIB develop bronchoconstriction during exercise.