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Use of integral and differential methods for the determination of L-dopa in pure form and pharmaceutical preparations
M I Helaleh1, N Rahman, R M Jamhour
1Department of Chemistry, Aligarh Muslim University, India.
Journal of Pharmaceutical and Biomedical Analysis
|December 31, 1997
Abstract:
A new simple and selective kinetic method for the determination of L-dopa, using differential and integral methods, is described. The spectrophotometric measurements were recorded by measuring the increase in absorbance at 300 nm. The concentration range was valid from 5-35 ppm. The complex ratio showed a (1:2) of L-dopa with respect to sodium hydroxide, with formation constant 5.06 x 10(6) and molar absorptivity of 3.85 x 10(3) l mol-1 cm-1.