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Midwest experience with moyamoya disease

M K Edwards-Brown1, J P Quets

  • 1Department of Radiology, Indiana University School of Medicine, Riley Hospital, Indianapolis 46202, USA.

Clinical Neurology and Neurosurgery
|December 31, 1997
PubMed
Summary

This study reviewed Moyamoya disease cases, finding 51 instances. Akin Moyamoya disease presented earlier, often linked to conditions like sickle cell disease.

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Area of Science:

  • Neurology
  • Epidemiology
  • Vascular Neurology

Background:

  • Moyamoya disease is a rare cerebrovascular disorder.
  • Understanding its epidemiology is crucial for diagnosis and treatment.

Purpose of the Study:

  • To assess the epidemiology of Moyamoya disease.
  • To identify associated conditions and demographic patterns.

Main Methods:

  • Retrospective review of 51 Moyamoya disease cases.
  • Classification into classic, probable, and akin Moyamoya disease.
  • Analysis of patient demographics, associated conditions, and age of presentation.

Main Results:

  • 51 cases identified: 30 classic, 9 probable, 12 akin.
  • Akin Moyamoya associated with sickle cell disease, Down's syndrome, trauma, radiation, and neurofibromatosis.
  • Mean age of presentation varied: 14 years (classic), 4 years (probable), 5 years (akin).

Conclusions:

  • Moyamoya disease exhibits diverse presentations and associations.
  • Early identification of akin Moyamoya disease is important due to associated conditions.
  • Epidemiological data provides insights into Moyamoya disease patterns in the Midwestern US.

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