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The main epidemiological, clinical and morphological features of moyamoya disease in Yugoslavia
L Borota1, R Bajic, S Marinkovic
1Department of Neuroradiology, Institute of Neurosurgery, Belgrade, Yugoslavia. olja@nomos.ius.bg.ac.yu
Abstract:
Over a period of 22 years, 31 Moyamoya cases have been recorded in Yugoslavia. In this group of the patients comprising four children and 27 adults, peak age incidence is in the third and fourth decades of life. Males and females have been almost equally affected. Familial cases or territorial clustering of the patients have not been noted. In most cases leading symptoms on admission were motor disturbances. In four patients unilateral involvement was observed while in 27 patients bilateral changes of the internal carotid artery were seen.
Insights
This study analyzed 31 Moyamoya disease cases in Yugoslavia over 22 years. The findings highlight peak incidence in adults, with motor disturbances as the primary symptom, and predominantly bilateral internal carotid artery changes.
Area of Science:
- Neurology
- Vascular Neurology
- Epidemiology
Background:
- Moyamoya disease is a rare cerebrovascular disorder.
- Understanding its epidemiology is crucial for diagnosis and management.
Purpose of the Study:
- To describe the epidemiological characteristics of Moyamoya disease in Yugoslavia.
- To identify demographic patterns and clinical presentations.
Main Methods:
- Retrospective analysis of 31 Moyamoya disease cases.
- Data collected over a 22-year period.
Main Results:
- 31 cases identified between 1960s-1980s.
- Peak incidence in the third and fourth decades; equal male/female ratio.
- Motor disturbances were the most common presenting symptom; 27/31 cases showed bilateral internal carotid artery changes.
Conclusions:
- Moyamoya disease in Yugoslavia presented with typical demographic and clinical features.
- The study underscores the importance of recognizing motor disturbances as a key symptom.