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[Syphilitic parenchymatous keratitis]

F Ignat1, L Davidescu

  • 1Clinica oftalmologică Craiova.

Oftalmologia (Bucharest, Romania : 1990)
|January 1, 1997
PubMed
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This case study highlights congenital syphilis (luetic) bilateral keratitis in a young man. Early diagnosis and Benzylpenicillinum kalicum treatment led to a spectacular recovery, emphasizing the importance of recognizing late syphilis complications.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Syphilology

Background:

  • Congenital syphilis can manifest with ocular and auditory symptoms.
  • Late-onset congenital syphilis (lues) may present with subtle signs.
  • Bilateral keratitis is a potential ocular manifestation of untreated syphilis.

Observation:

  • A 17-year-old male presented with luetic bilateral keratitis.
  • Clinical findings included high-positive VDRL, AT antigen presence, hearing loss, and dental anomalies.
  • The patient's mother had a negative VDRL but a positive AT test, suggesting late gestational syphilis.

Findings:

  • Congenital syphilis was diagnosed based on clinical presentation and serological tests.
  • Treatment with Benzylpenicillinum kalicum and Prednisone resulted in rapid improvement.

Related Experiment Videos

  • Ocular neovascularization resolved, and visual acuity returned to normal within six weeks.
  • Implications:

    • This case underscores the significance of considering congenital syphilis in young patients with unexplained bilateral keratitis.
    • Prompt and specific treatment is crucial for preventing long-term sequelae.
    • Awareness of late congenital syphilis and its varied presentations is vital for both medical and social management.