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[Nutritional support in bone marrow transplantation]
C Gómez Candela1, A I de Cos Blanco, M A Martínez Olmos
1Unidad de Nutrición Clínica y Dietética, Hospital Universitario La Paz, Madrid, España.
Nutricion Hospitalaria
|December 31, 1997
Summary
Nutritional support (NS) effectively maintains nutritional condition in bone marrow transplant (BMT) patients. Tailoring NS to the underlying disease and chemotherapy intensity is crucial for optimal outcomes.
Area of Science:
- Oncology
- Hematology
- Clinical Nutrition
Background:
- Bone marrow transplant (BMT) treatments can compromise patient nutritional status, increasing morbidity and mortality.
- Effective nutritional support (NS) is vital for managing BMT patients.
Purpose of the Study:
- To evaluate the efficacy of a nutritional support (NS) protocol for patients undergoing BMT.
- To assess the impact of NS on nutritional condition (NC) in BMT recipients.
Main Methods:
- 55 BMT patients (24 male, 31 female) were analyzed.
- Nutritional condition (NC) was assessed using anthropometric, biochemical, and immunological parameters.
- Total parenteral nutrition (TPN) was administered from the second post-transplant day until sufficient oral intake was achieved.
Main Results:
- Average TPN duration was 16 days, longer in leukemia patients (p < 0.05).
- NC showed no significant overall change, but albumin levels dropped significantly in leukemia (p < 0.05) and solid tumor (p < 0.01) patients.
- Acceptable oral ingestion (14.5%) correlated with better albumin maintenance (p < 0.05).
Conclusions:
- Nutritional support (NS) is effective in maintaining NC levels for BMT patients.
- Aggressive pre-BMT chemotherapy necessitates adapted NS, considering disease type and TPN duration.
- Oral ingestion may offer benefits for gastrointestinal health in BMT patients.