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Generation of Genetically Modified Mice through the Microinjection of Oocytes
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[Targeting the gene for platelet-derived growth factor A-chain (PDGF-A) and preparation of chimeric mice with a

I V Makarova, N S Neznanov, E S Tsymbaliuk

    Molekuliarnaia Genetika, Mikrobiologiia I Virusologiia
    |January 1, 1997
    PubMed

    Abstract:

    A vector was selected for homologous recombination to generate mouse embryonic stem cell clones with disrupted platelet-derived growth factor A (PDGF-A) chain gene. A chimeric mouse with targeted PDGF-A gene has been created.

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