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[Incidence and mortality of aortic dissection]
I Mészáros1, J Mórocz, J Szlávi
1Városi Kórház Belgyógyászati Osztály, Sümeg.
Orvosi Hetilap
|December 31, 1997
Summary
This population-based study found aortic dissection incidence increased over 24 years, with higher rates in women. Mortality was extremely high, especially in the first two days post-admission.
Area of Science:
- Cardiovascular Epidemiology
- Thoracic Aortic Disease
Context:
- A 24-year population-based study (1973-1996) examined aortic dissection in 106,000 inhabitants.
- Data included both inpatient and outpatient cases to determine incidence and mortality.
Purpose:
- To determine the incidence and mortality rates of aortic dissection within a defined population.
- To analyze trends in aortic dissection incidence over a 24-year period.
- To investigate demographic factors, such as age and sex, associated with aortic dissection.
Summary:
- 74 cases of aortic dissection were identified, with an overall incidence of 2.89%/year, increasing in the latter half of the study period.
- Women had a higher mean age at diagnosis (p < 0.05) and a higher male/female ratio of 1:1.6.
- Mortality was exceptionally high, with 18.9% dying before hospital admission and over 75% of inpatients dying within 48 hours.
Impact:
- The study suggests an underestimation of aortic dissection incidence in Hungary, potentially exceeding 3.0/100,000/year.
- Findings highlight the critical need for prompt diagnosis and intervention due to the disease's rapid and often fatal progression.
- Surgical intervention showed a perioperative mortality of 33.3%, with long-term survival rates of 50% at one month and 33.3% at three years.