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Updated: Aug 7, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
[QKD: a new parameter for clinical research on hypertension]
J L Palma Gámiz1, A Calderón Montero, M D Isasa Gay
1Servicio de Cardiología, Hospital Ramón y Cajal, Madrid. jlpalma@meditex.es
Abstract:
Structural and functional heart changes induced by hypertension are easily detected nowadays by ecocardiography-Doppler. Nevertheless, this diagnostic tool is less conclusive to evaluate the large arteries modifications during hypertension. High blood pressure induces from the beginning architectural changes in all artery beds, characterized by an increase in wall thickness, reversing secondary the ratio wall thickness/lumen radio. The increase in wall stiffness as a consequence of cellular hypertrophy and hyperplasia, modifies substantially both, distensibility and compliance, two major factors in determining the grade of left ventricular hypertrophy and performance. Evaluation of pulse wave velocity implemented with a new algorhythm (QKD) permits by non-invasive ambulatory long period of time method, an indirect approach to the arterial functional state in hypertension and aging, establishing in some instances, prognosis criteria, with an accuracy even better than that given by the 24-hour load pressure index.
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Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Hypertension and Regulation of Blood Pressure
Hypertension I: Introduction
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension IV: Drug Therapy and Lifestyle Modifications
Hypertension V: Nursing Management
