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[Sodium saccharin effect on the mice large intestine]
G Torres de Mercau1, N Riviera de Martínez Villa, H Vitalone
1Departmento Biomédico, Facultad de Medicina, Universidad de Tucumán.
Acta Gastroenterologica Latinoamericana
|January 1, 1997
Abstract:
Sodium saccharin has found to be a tumoral promoter in the rat's bladder epithelium, property not demonstrated in humans. Nevertheless, at present there's no references on the possible alterations produced by sodium saccharin in the epithelium of the mice colon. In this work we describe the alterations produced by low doses of sodium saccharin in the epithelium of the mice colon. The changer produced by sodium saccharin consist in pleomorphic microvill with variations of form, length diameter and curvature and demonstrate by transmission electron microscopy.