Spontaneous perforations of the small intestine
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Updated: Oct 31, 2026

Intravital Imaging of Intraepithelial Lymphocytes in Murine Small Intestine
Published on: June 24, 2019
J Waisberg1, S H Bromberg, M I Franco
1Department of Gastrointestinal Surgery, State Public Servant Hospital, São Paulo, Brazil.
Background And Methods:
The present study describes the procedures used by the authors in the management of 34 patients with spontaneous perforation of the small intestine.
Results:
Only one (2.9%) of the patients had the perforation cause diagnosed before laparotomy; 27 (80%) cases showed ileal perforative lesions while seven (20%) had jejunal lesions; 31 (91.1%) patients presented single perforations and three (8.8%) had multiple ones. Intestinal resection followed by anastomosis or ileostomy and colostomy, was carried out in 21 (61.7%) cases, and 13 (38.2%) patients were submitted to exeresis with edge restoration and lesion suture. The cause of perforation could be identified in 29 (86.3%) cases while in five (14.7%) patients the cause was considered idiopathic. Eighteen (53%) patients recovered from surgery and were discharged; there were 16 (47%) deaths resulting from a number of complications.
Conclusions:
Since the prognosis regarding this disease depends on the peritoneal infection severity level, the patient's organic resistance, and most of all, the time interval spent until the treatment is initiated, the authors emphasize the need to have a laparotomy performed as early as possible considering that this procedure provides the best chances of survival and health recovery.
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