Coil occlusion for patent ductus arteriosus in Japan
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Updated: Oct 31, 2026
Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
Published on: December 23, 2022
1Department of Pediatrics, School of Medicine, Sapporo Medical University, Japan.
Insights
Coil occlusion effectively treats patent ductus arteriosus in Japanese patients, achieving high closure rates. This minimally invasive procedure demonstrated a low complication rate, making it a viable treatment option.
Area of Science:
- Cardiology
- Interventional Cardiology
- Pediatric Cardiology
Background:
- Patent ductus arteriosus (PDA) is a common congenital heart defect.
- Coil occlusion is an alternative to surgical closure for PDA.
Purpose of the Study:
- To evaluate the outcomes of coil occlusion for PDA in Japan.
- To identify factors influencing successful coil occlusion and closure rates.
Main Methods:
- A nationwide survey of Japanese hospitals was conducted.
- Questionnaires collected data on 231 PDA coil occlusion procedures in 218 patients.
- Outcomes included implantation success, acute and late closure rates, and complications.
Main Results:
- Successful coil implantation was achieved in 94% of procedures.
- Acute complete closure occurred in 71% of successful implantations.
- Overall complete closure, including reocclusion, reached 89% with no life-threatening complications.
- Ductal diameter influenced outcomes: >3mm decreased implantation success, <2mm increased closure incidence.
Conclusions:
- Coil occlusion is a safe and effective treatment for PDA in Japan.
- Angiographic characteristics and ductal diameter are important considerations for procedural success.
- Further research into optimizing coil selection based on ductal morphology is warranted.
Abstract:
We surveyed Japanese experience of coil occlusion of patent ductus arteriosus up to 30 September 1996 by sending questionnaires to 175 hospitals. Thirty-four hospitals reported outcome data for 231 procedures in 218 patients. Successful implantation was achieved in 94% and acute complete closure of the ductus occurred in 71% of those in whom implantation of the coil was successful. Of the latter, 83% reported late complete closure. When those patients who underwent reocclusion for residual shunt are included, 89% attained complete closure. No life-threatening complications have occurred so far. Late reopening was reported in 3 cases. Although the angiographic type of ductus was significantly related to successful implantation (p < 0.01), there was no significant correlation with complete occlusion. Ductuses with a minimum diameter greater than 3 mm had a decreased chance of successful implantation, whereas those less than 2 mm had a greater incidence of complete closure.
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