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Infant botulism. The first culture-confirmed Danish case
T Balslev1, E Ostergaard, I K Madsen
1Department of Paediatrics, Aalborg Hospital, Denmark.
Neuropediatrics
|December 31, 1997
Summary
Infant botulism, a rare condition outside the USA, is caused by intestinal Clostridium botulinum colonization. This case highlights honey as a potential source, linking contaminated honey to infant botulism diagnosis and recovery.
Area of Science:
- Pediatric Neurology
- Infectious Diseases
- Gastroenterology
Background:
- Infant botulism is an intestinal illness caused by Clostridium botulinum, C. barati, or C. butyricum.
- Cases are rarely reported internationally, with most occurring in the United States.
Observation:
- A 3-month-old infant presented with constipation, lethargy, feeding issues, and severe, descending muscle weakness.
- The infant was breastfed and had also consumed honey.
- Symptoms resolved with supportive care.
Findings:
- Serum analysis confirmed the presence of Clostridium botulinum toxin types A-F.
- Stool samples revealed Clostridium botulinum producing toxin types A and E.
- The same bacterial strain was identified in a honey jar of the same brand fed to the infant.
Implications:
- This case underscores honey as a potential environmental reservoir and source for infant botulism.
- Highlights the importance of considering non-US sources in infant botulism etiology.
- Suggests careful consideration of honey consumption in infants diagnosed with botulism.