Acylation stimulating protein and the adipocyte

ASP constitutes a metabolic bridge integrating events in the circulation with the adipocyte microenvironment and regulation of a key adipose function-storage of fat. Dysregulation of the ASP pathway may have important metabolic consequences and may be associated with both obesity on one hand and cardiovascular disease on the other hand. Clearly, many in vitro and in vivo studies remain to be done to establish clearly such links and future work on ASP promises to be both exciting and rewarding.