Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The ageing brain: normal and abnormal memory

M S Albert1

  • 1Massachusetts General Hospital, Charlestown, MA 02129, USA.

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
|January 7, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lessons to Be Learned about Clinical Trials in Preclinical AD from Ongoing Longitudinal Studies.

The journal of prevention of Alzheimer's disease·2017
Same author

'Alzheimer's Progression Score': Development of a Biomarker Summary Outcome for AD Prevention Trials.

The journal of prevention of Alzheimer's disease·2017
Same author

Entorhinal Cortex: Antemortem Cortical Thickness and Postmortem Neurofibrillary Tangles and Amyloid Pathology.

AJNR. American journal of neuroradiology·2017
Same author

Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway.

Molecular psychiatry·2016
Same author

Semiautomatic segmentation of ventilated airspaces in healthy and asthmatic subjects using hyperpolarized 3He MRI.

Computational and mathematical methods in medicine·2013
Same author

Correlations between MRI white matter lesion location and executive function and episodic memory.

Neurology·2011
Same journal

The microlandscapes of tree trunks: the effect of lichen and tree-level characteristics on arthropod communities.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same journal

Centimetre-scale landscapes to assess the motion behaviour and cognition of gastropods and bivalves.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same journal

Intertidal microcosms of wave-swept rocky shores: ecological and physiological insights from a uniquely stressful environment.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same journal

Temporal and spatial variation in temperature and oxygen at the microscale: key niche axes for aquatic life.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same journal

Natural microcosms in ecology: fulfilling the promise of model systems?

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same journal

Microbe-induced galls and plant defence: metabolite crosstalk in a co-evolutionary battle.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
See all related articles

Healthy aging involves brain changes affecting memory, distinct from Alzheimer's disease. Understanding these age-related memory differences is key for developing effective interventions.

Area of Science:

  • Neuroscience
  • Gerontology
  • Cognitive Psychology

Background:

  • Cognitive decline, particularly in learning and memory, is common with advanced age.
  • Brain structure and function undergo significant alterations in older adults.

Purpose of the Study:

  • To examine age-related changes in brain structure and function.
  • To differentiate these changes from early-stage dementia, such as Alzheimer's disease.
  • To explore implications for intervention strategies.

Main Methods:

  • Neuroimaging techniques to assess brain structure.
  • Cognitive assessments to evaluate memory and learning.
  • Comparative analysis of healthy aging versus early dementia.

Main Results:

Related Experiment Videos

  • Significant brain changes correlate with memory alterations in healthy aging.
  • Age-related cognitive and neurobiological changes differ markedly from Alzheimer's disease pathology.

Conclusions:

  • Age-related memory decline has a distinct neurobiological profile compared to dementia.
  • This distinction is crucial for designing targeted interventions for older adults.