Related Experiment Videos
[Importance and physiologic nutritional requirement of the selenium trace element within the scope of parenteral
1HPN-Centrum, Klinikum Franklin, Freien Universität Berlin. gramm@zop_admin.ukbf.fu-berlin.de
Medizinische Klinik (Munich, Germany : 1983)
|January 7, 1998
Abstract
Basis:
Selenium-responsive clinical manifestations of selenium deficiency and elucidation of the biochemical and molecular biological basis of the essentiality of selenium give evidence for the biological importance of the trace element in human nutrition.
Conclusion:
The dietary parenteral selenium requirement can be calculated on the basis of the maximal gene expression of the selenoprotein plasma glutathione peroxidase (plGPx). In total parenteral nutrition a daily requirement of 0.01 mumol/kg body weight for adults and 0.025 mumol/kg body weight for children can be seen as adequate and safe.