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[Selenium, antioxidant status and radical/reactive oxygen species in medicine]
1Institut für Klinische Chemie, Friedrich-Schiller-Universität, Jena.
Medizinische Klinik (Munich, Germany : 1983)
|January 7, 1998
Abstract
Background:
In all organisms with a metabolism of oxygen, radicals/reactive oxygen species appear. Normally a balance exists between formation and destruction of radicals. Many diseases show a disturbance of this balance with the destruction of biological structures. Results in patients with sepsis, terminal renal failure, bone marrow transplantation and cancer are given.
Conclusion:
To avoid a possible pro-oxidative effect (vitamins C and E) and intoxications (selenium), before substitution a monitoring is necessary.