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Cloning and characterization of the lytB gene of Campylobacter jejuni
M M Wösten1, E E Ishiguro, B A van der Zeijst
1Department of Bacteriology, Faculty of Veterinary Medicine, Universiteit Utrecht, The Netherlands.
FEMS Microbiology Letters
|January 7, 1998
Abstract:
LytB of Escherichia coli is an essential gene involved in penicillin tolerance and the stringent response. The lytB gene of Campylobacter jejuni was cloned and characterized. It could complement a temperature-sensitive E. coli lytB mutant. The C. jejuni lytB gene encodes a protein of 277 amino acids that has 34, 36 and 40% amino acid identity with the LytB proteins of E. coli, Haemophilus influenzae, and Synechocystis sp. PCC6803, respectively. The lytB gene is situated between the aroA gene and a gene that encodes ribosomal protein S1.