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[Gram-negative enteric bacteremia in children in the Negev (1989-1994)]
M Maimon-Greenwald1, E Leibovitz, N Maimon
1Pediatric Infectious Disease Unit, Soroka Medical Center, Beer Sheba.
Abstract:
During 1989-1994, there were 322 episodes of Gram-negative enteric bacteremia in 308 children. The incidence increased from 31/100,000 in children younger than 15 years of age during 1989-1991, to 50/100,000 during 1992-1994. The most common pathogens were Klebsiella, E. Coli, Salmonella and Enterobacter. 39% of episodes were nosocomial and a significant increase was recorded for each species during the last 3 years of the study. Klebsiella represented the most common pathogen causing nosocomial bacteremia, while E. coli and Salmonella were the main pathogens causing community-acquired bacteremia. In this study in southern Israel, the incidence of Gram-negative enteric bacteremia was significantly higher in Bedouin children, with the exception of bacteremia due to Salmonella, which occurred mainly in Jewish children.
Insights
Gram-negative enteric bacteremia incidence rose in children under 15. Klebsiella and E. coli were common pathogens, with higher rates in Bedouin children.
Area of Science:
- Pediatric Infectious Diseases
- Microbiology
- Epidemiology
Context:
- This study analyzed 322 episodes of Gram-negative enteric bacteremia in 308 children in southern Israel between 1989 and 1994.
- The incidence of bacteremia increased significantly over the study period.
Purpose:
- To investigate the incidence, pathogens, and risk factors of Gram-negative enteric bacteremia in children.
- To compare bacteremia rates between different ethnic groups in southern Israel.
Summary:
- The incidence of Gram-negative enteric bacteremia in children younger than 15 increased from 31/100,000 to 50/100,000 between 1989-1991 and 1992-1994.
- Common pathogens included Klebsiella, E. coli, Salmonella, and Enterobacter, with Klebsiella being the most frequent cause of nosocomial infections and E. coli and Salmonella of community-acquired infections.
- A significantly higher incidence of Gram-negative enteric bacteremia was observed in Bedouin children compared to Jewish children, except for Salmonella bacteremia.
Impact:
- Highlights the rising trend of Gram-negative enteric bacteremia in pediatric populations.
- Identifies key pathogens and differentiates their roles in nosocomial versus community-acquired infections.
- Reveals significant ethnic disparities in bacteremia incidence, underscoring the need for targeted public health interventions.