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Does hydrosalpinx reduce the pregnancy rate after in vitro fertilization?
1Department of Obstetrics and Gynecology, Poissy Hospital, University of Paris V, France.
Objective:
To determine the effect of hydrosalpinges on the pregnancy rate in an IVF program.
Design:
Multicentric retrospective analysis of clinical and laboratory data.
Setting:
Two assisted reproductive technology centers in university hospitals.
Patient(S):
Four hundred forty-three women, under 38 years of age, with pure tubal infertility. The patients were classified into the following five groups: bilateral hydrosalpinges (n = 37), unilateral hydrosalpinx (n = 54), bilateral tubal occlusion (n = 207), unilateral tubal occlusion (n = 55), and severe tubal disease without complete occlusion (n = 90).
Main Outcome Measure(S):
Pregnancy and implantation rates.
Result(S):
The pregnancy and the implantation rates per transfer (12.3% and 5.4%) obtained by women with bilateral hydrosalpinges are significantly lower than the rates (means = 23.1% and 12%) for all other tubal infertility groups.
Conclusion(S):
Bilateral hydrosalpinges have a deleterious effect on the outcome of IVF program.