Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Terbinafine: an update

A K Gupta1, N H Shear

  • 1Department of Medicine, Sunnybrook Health Science Center, Toronto, Canada.

Journal of the American Academy of Dermatology
|January 7, 1998
PubMed
Summary
This summary is machine-generated.

Oral terbinafine, approved in 1996 for onychomycosis, has treated millions worldwide. This review examines its effectiveness and safety profile for fungal skin infections.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Peripheral edema due to nifedipine-itraconazole interaction: a case report.

Archives of dermatology·1996
Same author

High frequency 40-MHz ultrasound. A possible noninvasive method for the assessment of the boundary of basal cell carcinomas.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·1996
Same author

Effect of ionizing radiation on AP-1 binding activity and basic fibroblast growth factor gene expression in drug-sensitive human breast carcinoma MCF-7 and multidrug-resistant MCF-7/ADR cells.

The Journal of biological chemistry·1995
Same author

Role of cellular casein kinase II in the function of the phosphoprotein (P) subunit of RNA polymerase of vesicular stomatitis virus.

The Journal of biological chemistry·1995
Same author

Fundus imaging in patients with cataract: role for a variable wavelength scanning laser ophthalmoscope.

The British journal of ophthalmology·1995
Same author

Age and gender differences in the impact of psoriasis on quality of life.

International journal of dermatology·1995
Same journal

Comparative Alopecia Outcomes After Copper and Hormonal Intrauterine Device Placement: A TriNetX Database Retrospective Cohort Study.

Journal of the American Academy of Dermatology·2026
Same journal

Uncovering a Dual Th17/Type 2 Transcriptomic Endotype in Psoriasis.

Journal of the American Academy of Dermatology·2026
Same journal

Dermatologic conditions associated with HIV among US adults across different racial and ethnic groups: A retrospective cohort study using TriNetX.

Journal of the American Academy of Dermatology·2026
Same journal

Ethical Considerations in Same-Day Surgical Treatment of a High-Risk, Poorly Differentiated Squamous Cell Carcinoma.

Journal of the American Academy of Dermatology·2026
Same journal

The Ethics of the Handshake in Dermatology.

Journal of the American Academy of Dermatology·2026
Same journal

Dermatology images: Hidradenitis suppurativa.

Journal of the American Academy of Dermatology·2026
See all related articles

Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Oral terbinafine was introduced in the UK in 1991 and approved in the US in 1996 for onychomycosis.
  • By December 1996, an estimated 4 million patients globally had received oral terbinafine treatment.

Purpose of the Study:

  • To review the efficacy of oral terbinafine in treating onychomycosis (fungal nail infection).
  • To evaluate the safety and adverse-effects profile of oral terbinafine therapy.
  • To assess the drug's utility for other dermatomycoses (fungal skin infections).

Main Methods:

  • Literature review of published studies on oral terbinafine.
  • Analysis of clinical trial data regarding efficacy and adverse events.
  • Examination of post-marketing surveillance data.

Related Experiment Videos

Main Results:

  • Oral terbinafine demonstrates significant efficacy in treating onychomycosis.
  • The drug is also effective against various other dermatomycoses.
  • The adverse-effects profile of oral terbinafine is generally well-tolerated, with specific side effects noted.

Conclusions:

  • Oral terbinafine is an effective treatment option for onychomycosis and other fungal skin infections.
  • Understanding its efficacy and adverse effects is crucial for clinical application.
  • The widespread use of oral terbinafine highlights its importance in managing dermatomycoses.