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Long-term stability of a cyanmethemoglobin reference standard
The American Journal of Medical Technology
|July 1, 1976
Summary
A 1974 analysis showed a 1966 cyanmethemoglobin standard remained suitable for hemoglobin assays. This suggests current one-year expiration dates for commercial standards may be unnecessarily short.
Area of Science:
- Clinical Chemistry
- Hematology
Background:
- Cyanmethemoglobin standards are crucial for accurate hemoglobin assays.
- Current commercial standards have a one-year expiration period.
Purpose of the Study:
- To evaluate the long-term stability of a cyanmethemoglobin secondary standard.
- To assess the feasibility of extending expiration times for hemoglobin standards.
Main Methods:
- A comparative analysis was conducted in late 1974.
- The stability of a cyanmethemoglobin secondary standard prepared in 1966 was assessed.
Main Results:
- The 1966 cyanmethemoglobin standard was found to be still suitable for use in hemoglobin assays.
- The standard demonstrated stability over a period of at least eight years.
Conclusions:
- The findings suggest that the one-year expiration time for commercial cyanmethemoglobin standards may be extended.
- Extended expiration dates could lead to cost savings and reduced waste in laboratory settings.