Partition coefficients of methyl tert-butyl ether (MTBE)

The knowledge of the partition coefficients between the air and arterial blood and between the blood and the different physiological compartments of the body are essential to the mathematical modelling of the respiratory uptake and elimination of toxic vapours. Partition coefficients of methyl tertbutyl ether (MTBE) in saline, olive oil, urine and human blood, and various rat tissues were calculated after gas-chromatographic quantification of MTBE in the air phase. The blood/air, urine/air saline/air, fat/air and oil/air partition coefficients (lambda) are respectively: 20.0, 15.6, 15.3, 142.0 and 138.