Protocol for the pathologic examination and tissue processing of the mammographically directed breast biopsy

Achieving the maximum yield of breast cancers detected by mammography has required certain changes in tissue handling and examination of the mammographically directed breast biopsy. This new radiographic technique, increased use of breast-conserving surgical approaches for the treatment of breast cancer, more enlightened and demanding patients, and increasing medical-legal exposure have all contributed to changes in the way surgical pathologists should process and sample breast biopsy specimens.