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Ectopic prostatic tissue in the uterine cervix

O Larraza-Hernandez1, K H Molberg, G Lindberg

  • 1Department of Pathology, Hospital PEMEX, Mexico City, Mexico.

International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists
|July 1, 1997
PubMed
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The first reported case of ectopic prostatic tissue in the uterine cervix was found in a 38-year-old woman. This benign finding, identified by specific markers, could be mistaken for other cervical conditions.

Area of Science:

  • Gynecologic Pathology
  • Urologic Pathology
  • Histopathology

Background:

  • Ectopic prostatic tissue is rare, with most cases occurring in the female reproductive tract.
  • Differential diagnosis of cervical lesions includes various benign and malignant conditions.

Observation:

  • A 38-year-old woman presented with a unique finding of benign prostatic glands in the uterine cervix.
  • The ectopic tissue exhibited cribriform and papillary patterns with squamous metaplasia.

Findings:

  • Immunohistochemical staining confirmed the prostatic origin, showing reactivity for prostatic specific antigen (PSA) and prostatic specific acid phosphatase (PSAP).
  • The lesion was confirmed as benign ectopic prostatic tissue, not indicative of malignancy.

Implications:

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  • This case highlights the importance of considering rare diagnoses in cervical pathology.
  • Accurate identification is crucial to avoid misdiagnosis, particularly distinguishing it from microglandular hyperplasia, mesonephric rests, or adenocarcinoma in situ.
  • The finding may represent an embryonic rest, offering insights into developmental anomalies.