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Updated: Aug 19, 2026

The Influence of Liver Resection on Intrahepatic Tumor Growth
Published on: April 9, 2016
Fibrolamellar hepatocellular carcinoma: results of partial liver resection
A Martínez Isla1, A Ferrara, J M Badia
1Department of Surgery, Royal Postgraduate Medical School, Hammersmith Hospital, London.
Aim:
To assess the results of partial hepatic resection in the treatment of fibrolamellar hepatocellular carcinoma.
Patients And Results:
We present six cases of Fibrolamellar hepatocellular carcinoma treated by partial hepatic resection. There were five females and one male with a mean age of 20 (2.6) yr. Five patients were stage IVA and 1 IVB based on the Union International Against Cancer Classification. Two patients, due to recurrent disease, needed further pulmonary resection and a hilar lymphadenectomy. All six cases underwent major resection, three with vascular reconstruction. No operative mortality was recorded; half of the patients displayed some degree of morbidity. One patient died six months after the operation and the rest are alive at 78, 41, 24, 12 and 9 months. We believe that even in advanced cases, an aggressive surgical policy even with vascular reconstruction is justified in patients with fibrolamellar hepatocellular carcinoma.

