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Posthypoxic myoclonus in intensive care

O Miró1, A Chamorro, M del Mar Lluch

  • 1Department of Internal Medicine, Hospital Clínic i Provincial, Barcelona, Spain.

European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine
|September 1, 1994
PubMed
Summary

Posthypoxic myoclonus, or Lance-Adams syndrome, is a rare condition after cardiac arrest. Early diagnosis and treatment with clonazepam can improve outcomes for this movement disorder.

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Area of Science:

  • Neurology
  • Critical Care Medicine

Background:

  • Posthypoxic myoclonus (Lance-Adams' syndrome) is a rare neurological complication following cardiorespiratory arrest.
  • It presents a better prognosis compared to other movement disorders resulting from brain ischemia.

Observation:

  • A case of posthypoxic myoclonus is presented in a 66-year-old woman after acute myocardial infarction and cardiopulmonary arrest.
  • The patient exhibited action and intention myoclonus, exacerbated by acoustic and pain stimuli.

Findings:

  • The myoclonus was likely of subcortical origin.
  • Treatment with clonazepam (2 mg three times daily) resulted in improvement of the myoclonic movements.

Implications:

  • Early diagnosis of posthypoxic myoclonus in intensive care units is crucial.

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  • Prompt and appropriate treatment can prevent misinterpretation and manage this specific movement disorder effectively.