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Related Experiment Videos

[Right-sided infective endocarditis with ventricular septal defect]

N Sasahashi1, F Ando, F Okamoto

  • 1Department of Cardiovascular Surgery, Hyogo Kenritsu Amagasaki Hospital.

Rinsho Kyobu Geka = Japanese Annals of Thoracic Surgery
|February 1, 1994
PubMed
Summary
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Surgical treatment for infective endocarditis with ventricular septal defect (VSD) involving Peptostreptococcus infection was successful in two patients. Early surgical intervention with vegetation excision and defect repair led to uneventful recovery.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Surgical Treatment

Background:

  • Infective endocarditis (IE) with ventricular septal defect (VSD) requires timely management.
  • Peptostreptococcus is a causative agent in some IE cases.
  • Surgical intervention is often necessary for complex VSD and IE.

Observation:

  • Two patients with right-sided IE and VSD caused by Peptostreptococcus presented for surgical treatment.
  • Echocardiography identified vegetations in both patients: one on the chordae tendineae and the other on the tricuspid leaflet.
  • Both patients underwent surgery after antibiotic therapy during a non-active phase of infection.

Findings:

  • Case 1: A 7-year-old girl underwent direct VSD closure and vegetation excision.
  • Case 2: A 22-year-old female had partial leaflet excision, autopericardial patch plasty for the tricuspid valve, and direct VSD closure.

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  • Both patients received 6 weeks of postoperative intravenous antibiotics and experienced uneventful clinical courses.

    • Implications:

    • Local vegetation excision and autopericardial patch plasty are effective for VSD with localized vegetations and minor valvular regurgitation.
    • Aggressive surgical management can lead to successful outcomes in complex IE and VSD cases.
    • This approach highlights the importance of tailored surgical strategies based on vegetation characteristics and valvular involvement.