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Rubiadin, a new antioxidant from Rubia cordifolia
Y B Tripathi1, M Sharma, M Manickam
1Department of Medicinal Chemistry, Banaras Hindu University, Varanasi, India.
Indian Journal of Biochemistry & Biophysics
|June 1, 1997
Abstract:
Rubiadin, a dihydroxy anthraquinone, isolated from alcoholic extract of Rubia cordifolia, possesses potent antioxidant property. It prevents lipid peroxidation induced by FeSO4 and t-butylhydroperoxide (t-BHP) in a dose dependent manner. The per cent inhibition was more in the case of Fe2+ induced lipid peroxidation. The antioxidant property of the preparation has been found to be better than that of EDTA, Tris, mannitol, Vitamin E and p-benzoquinone.