Related Experiment Videos
Resorbable versus nonresorbable membranes in combination with Bio-Oss for guided bone regeneration
N U Zitzmann1, R Naef, P Schärer
1Department of Fixed and Removable Prosthodontics and Dental Materials, University of Zurich, Switzerland.
The International Journal of Oral & Maxillofacial Implants
|January 13, 1998
Summary
Bio-Gide, a resorbable collagen membrane, shows comparable results to expanded polytetrafluoroethylene (Gore-Tex) for guided bone regeneration. Bio-Gide offers a viable alternative with fewer complications like wound dehiscence.
Area of Science:
- Dental Implantology
- Biomaterials Science
- Regenerative Medicine
Background:
- Guided bone regeneration (GBR) is crucial for dental implant success.
- Exposed implant surfaces present challenges in GBR.
- Comparing resorbable and non-resorbable membranes is essential for optimizing GBR outcomes.
Purpose of the Study:
- To compare the efficacy of Bio-Gide (resorbable collagen membrane) versus expanded polytetrafluoroethylene (ePTFE, Gore-Tex) membranes for GBR.
- To evaluate bone fill and complication rates in GBR with exposed implant surfaces.
Main Methods:
- A 2-year split-mouth clinical investigation involving 25 patients.
- 84 defects were treated with Bio-Oss bone graft and covered with either Bio-Gide or Gore-Tex membranes.
- Defect dimensions and morphology were measured pre- and post-treatment.
Main Results:
- Statistically significant bone fill was observed with both membranes (P < .0001).
- No significant difference in bone fill was found between Bio-Gide (92%) and Gore-Tex (78%) groups (P > .94).
- Gore-Tex group experienced 44% wound dehiscence and/or premature membrane removal.
Conclusions:
- Bio-Gide serves as a effective alternative to ePTFE membranes in GBR procedures.
- The resorbable nature of Bio-Gide may reduce complications associated with non-resorbable membranes.