Related Experiment Video

Updated: Aug 5, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 18, 2011

Chronic aspiration in children

L N Murray1, J L Guarisco

  • 1Tulane University Medical Center, New Orleans, USA.

The Journal of the Louisiana State Medical Society : Official Organ of the Louisiana State Medical Society
|January 13, 1998
PubMed

Insights

Chronic aspiration in children poses severe pulmonary risks and necessitates thorough assessment for effective treatment. Surgical interventions, including laryngotracheal separation, can be life-saving for severe cases unresponsive to other therapies.

Area of Science:

  • Pediatric Pulmonology
  • Pediatric Gastroenterology
  • Pediatric Otolaryngology

Background:

  • Chronic aspiration in children can lead to serious pulmonary complications, frequent hospitalizations, and significant healthcare costs.
  • Accurate diagnosis of aspiration causes is crucial for effective management.
  • While various medical and surgical options exist, some children with severe neurological disorders remain at high risk.

Purpose of the Study:

  • To review the causes, consequences, and management strategies for chronic aspiration in children.
  • To highlight the role of interventions, including surgical options, in controlling aspiration.
  • To emphasize the life-saving potential of laryngotracheal separation in refractory cases.

Main Methods:

  • Literature review of pediatric aspiration cases.
  • Analysis of treatment outcomes for medical and surgical interventions.
  • Case study review of children with severe neurological disorders and aspiration.

Main Results:

  • Aspiration etiology is diverse and requires precise assessment.
  • Medical and surgical treatments can effectively manage aspiration in many children.
  • Laryngotracheal separation is a viable, life-saving option for severe, persistent aspiration.

Conclusions:

  • Comprehensive evaluation is key to optimizing treatment for pediatric aspiration.
  • A range of interventions, from conservative to surgical, can control aspiration.
  • Laryngotracheal separation offers a critical solution for life-threatening aspiration unresponsive to other measures.

More Related Videos

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice15:43

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Published on: March 18, 2014

Open Tracheostomy Gastric Acid Aspiration Murine Model of Acute Lung Injury Results in Maximal Acute Nonlethal Lung Injury09:16

Open Tracheostomy Gastric Acid Aspiration Murine Model of Acute Lung Injury Results in Maximal Acute Nonlethal Lung Injury

Published on: February 26, 2017

Related Concept Videos

Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Chronic Obstructive Pulmonary Disease I: Introduction01:23

Chronic Obstructive Pulmonary Disease I: Introduction

Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...