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Updated: Aug 13, 2026

Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR
Published on: April 8, 2013
Anterolateral muscle bundle of the left ventricle, bulboventricular flange and subaortic stenosis
Insights
A newly identified muscle bundle in the left ventricle, present in 40% of normal hearts, may obstruct blood flow. This anterolateral muscle bundle is a potential remnant from embryonic development.
Area of Science:
- Cardiovascular Anatomy
- Embryology
- Cardiac Physiology
Background:
- The left ventricular outflow tract (LVOT) is critical for cardiac function.
- Anatomical variations in the LVOT can impact hemodynamics.
- Detailed understanding of cardiac muscle structures is essential for diagnosing potential pathologies.
Purpose of the Study:
- To describe a previously unrecognized muscle bundle in the LVOT.
- To investigate the prevalence and potential functional significance of this muscle bundle.
- To explore the embryological origins of the identified cardiac structure.
Main Methods:
- Anatomical dissection of human hearts.
- Histological examination of cardiac tissue.
- Embryological correlation and literature review.
Main Results:
- A distinct anterolateral muscle bundle was identified in the LVOT, situated between the left coronary aortic semilunar cusp and the anterior mitral leaflet.
- This muscle bundle was present in approximately 40% of the examined normal hearts.
- The muscle bundle's prominence can lead to obstruction in both the left ventricular inflow and outflow tracts.
Conclusions:
- The identified anterolateral muscle bundle represents a significant anatomical finding in the human heart.
- Its presence, particularly when prominent, can cause left ventricular inflow and outflow obstruction.
- Embryological evidence suggests this bundle is a remnant of the bulboatrioventricular flange, offering insights into cardiac development.
Abstract:
A hitherto unrecognized muscle bundle in the left ventricular outflow tract is described. Found between the left coronary aortic semilunar cusp and the anterior leaflet of the mitral valve, this anterolateral muscle bundle of the left ventricle is present in approximately 40 percent of normal hearts. On embryologic grounds it is suggested that this bundle is a muscular remnant of the left extremity of the bulboatrioventircular flange. It can be very prominent, causing obstruction of both the left ventricular inflow and outflow tracts.
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