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Bioactive iridoids and a new lignan from Allamanda cathartica and Himatanthus fallax from the Suriname rainforest
M S Abdel-Kader1, J Wisse, R Evans
1Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg 24061-0212, USA.
Journal of Natural Products
|January 15, 1998
Abstract:
Bioassay-guided fractionation of the EtOAc extract of both Allamanda cathartica and Himatanthus fallax (Apocynaceae) using the Sc-7 yeast strain resulted in the isolation of the weakly cytotoxic isoplumericin and plumericin. In addition, the new lignan 7(R)-methoxy-8-epi-matairesional and three known compounds, plumieride, matairesinol, and pinoresinol, were isolated from H. fallax.