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Noninvasive ventilation via bilevel positive airway pressure support in pediatric practice
R Padman1, S T Lawless, R G Kettrick
1Department of Pediatrics, duPont Hospital for Children, Wilmington, DE 19899, USA.
Insights
Bilevel positive airway pressure support effectively reduced respiratory rates and improved oxygenation in critically ill children, with only an 8% intubation rate. This noninvasive ventilation is recommended for pediatric intensive care units.
Area of Science:
- Pediatric Critical Care Medicine
- Respiratory Physiology
- Noninvasive Ventilation
Background:
- Critically ill children with underlying conditions often experience respiratory failure.
- Effective management of impending respiratory failure is crucial in pediatric intensive care units (PICUs).
- Noninvasive ventilation strategies are increasingly explored for pediatric respiratory support.
Purpose of the Study:
- To assess the efficacy of bilevel positive airway pressure (BiPAP) support in critically ill children.
- To evaluate the impact of BiPAP on respiratory parameters and oxygenation.
- To determine the rate of intubation in patients receiving BiPAP for respiratory insufficiency.
Main Methods:
- A prospective clinical study was conducted in a pediatric intensive care unit.
- Thirty-four children (6 months to 20 years) with impending respiratory failure were enrolled.
- Each patient served as their own control, receiving BiPAP ventilation.
Main Results:
- BiPAP significantly decreased dyspnea scores, resting heart rate, and respiratory rate.
- Room air oxygen saturation increased significantly, and bicarbonate concentrations improved.
- Only 8% of patients (3 out of 34) required subsequent artificial airway placement.
Conclusions:
- Bilevel positive airway pressure support demonstrated significant efficacy in improving respiratory and oxygenation parameters in critically ill children.
- The low rate of intubation suggests BiPAP is a valuable noninvasive option for selected pediatric patients.
- The findings support the integration of BiPAP into standard care protocols within pediatric ICUs.
Objective:
To evaluate the efficacy of bilevel positive airway pressure support in critically ill children with underlying medical conditions.
Design:
Prospective, clinical study.
Setting:
Pediatric intensive care unit (ICU).
Patients:
Thirty-four patients (6 mos to 20 yrs, mean 11.06 +/- 0.9 yrs) with impending respiratory failure were enrolled in the study. All patients required airway or oxygenation/ventilation support (awake or asleep) and required admission to our pediatric ICU. Each patient served as his or her own control. Exclusion criteria were absent cough or gag reflex, multiple organ system failure, age of <6 mos, vocal cord paralysis, and noncooperation with nasal mask.
Interventions:
Bilevel positive airway pressure support ventilation.
Measurements And Main Results:
Thirty-four patients with 35 episodes of respiratory insufficiency requiring airway support or oxygenation/ventilatory support were treated with bilevel positive airway pressure support ventilation. Dyspnea score decreased at least two deviations in all patients; dyspnea score decreased five deviations in 67% of patients. Resting heart rate decreased from 126 +/- 3.2 to 102 +/- 3.2 beats/min (p < .001), respiratory rate decreased from 39 +/- 3 to 25 +/- 1 breaths/min (p < .004), bicarbonate concentrations decreased from 30.0 +/- 1.0 to 24.0 +/- 0.7 mmol/L (p < .01), and room air saturation increased from 85 +/- 2% to 97 +/- 1%. Bilevel positive airway pressure support ventilation failure was characterized by an inability to stabilize progression of respiratory failure and the subsequent placement of an artificial airway. Three patients required placement of an artificial airway.
Conclusions:
A decrease in respiratory rate, heart rate, and dyspnea score and an improvement in oxygenation were noted in >90% of patients studied, resulting in only an 8% frequency of intubation. The efficacy of bilevel positive airway pressure support ventilation in selected groups of patients indicates the need to include this form of noninvasive pressure support ventilation in the care offered by pediatric ICUs.
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