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Anterior visual pathway gliomas

C R Thompson1, S Lessell

  • 1Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston 02114, USA.

International Ophthalmology Clinics
|January 16, 1998
PubMed
Summary
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Benign anterior visual pathway gliomas are controversial but rarely fatal. Malignant gliomas are uniformly fatal, with no effective treatments. Multidisciplinary care led by neuro-ophthalmologists is recommended for benign gliomas.

Area of Science:

  • Neuro-ophthalmology
  • Neuro-oncology
  • Pediatric Neurology

Background:

  • Benign anterior visual pathway gliomas present diagnostic and therapeutic challenges.
  • While low-grade, these tumors can cause significant visual loss and, rarely, death.
  • Malignant variants are uniformly fatal, despite aggressive treatment.

Purpose of the Study:

  • To review the controversies and current understanding of benign anterior visual pathway gliomas.
  • To highlight the challenges in managing these rare tumors.
  • To emphasize the role of a multidisciplinary team in patient care.

Main Methods:

  • Review of existing literature and clinical experience.
  • Discussion of diagnostic criteria and treatment options.

Related Experiment Videos

  • Emphasis on the leadership role of neuro-ophthalmologists.

    • Main Results:

    • Benign gliomas are neoplasms with low growth potential, but visual morbidity is common.
    • Hydrocephalus may occur, necessitating shunting.
    • The optimal treatment for non-hydrocephalic benign gliomas remains undetermined.
    • Malignant gliomas are rare and have a fatal outcome.

    Conclusions:

    • A multidisciplinary approach, led by neuro-ophthalmologists, is crucial for managing benign anterior visual pathway gliomas.
    • Further research, potentially through randomized controlled trials, is needed to establish optimal treatment strategies.
    • Malignant anterior visual pathway gliomas have a poor prognosis despite current therapies.