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Concordance for cloacal dysgenesis
R L Kramer1, M P Johnson, F Qureshi
1Department of Obstetrics and Gynecology, Hutzel Hospital/Wayne State University, Detroit, Mich. 48201, USA.
Fetal Diagnosis and Therapy
|January 16, 1998
Abstract:
Monozygotic (MZ) twins concordant for cloacal dysgenesis were diagnosed at 15 weeks' gestation on ultrasound exam. The structural alterations result from abnormal morphogenesis of the cloacal membrane and contiguous anlage with resultant secondary changes. These defects are suggestive of teratogen exposure or an endogenous event early in gestation, resulting in MZ twinning and the development of a polytopic field defect.