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Radiation dosimetry for indium-111-pentetreotide
M G Stabin1, P P Kooij, W H Bakker
1Oak Ridge Institute for Science and Education, Tennessee 37831-0117, USA.
Abstract
Unlabelled:
We present radiation dose estimates for 111In-pentetreotide.
Methods:
Kinetic data were gathered in 10 subjects at two different sites. A compartmental model was used to fit the data, including retention, in three major organs and excretion.
Results:
The data were consistent for the subjects at both sites. The organ receiving the highest dose was the kidneys (0.52 mGy/MBq); the effective dose equivalent was 0.1 mSv/MBq, and the effective dose was 0.073 mSv/MBq.
Conclusion:
The results of this study provide the basis for evaluation of radiation safety of this drug.