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Systemic treatment of severe psoriasis
K E Georgouras1, S S Zagarella, G D Cains
1University of New South Wales, Sydney, Australia.
The Australasian Journal of Dermatology
|February 12, 1998
Summary
Severe psoriasis is challenging to treat. This review reappraises established therapies like methotrexate and phototherapy, and discusses newer options such as cyclosporine, focusing on Australian dermatologists
Area of Science:
- Dermatology
- Immunology
Background:
- Severe psoriasis poses significant therapeutic challenges for dermatologists.
- Established treatments require reassessment, while newer options need careful consideration.
Purpose of the Study:
- To review and reappraise therapeutic modalities for severe psoriasis.
- To focus on treatments available to dermatologists in Australia.
Main Methods:
- Literature review of established and emerging psoriasis treatments.
- Focus on clinical applicability and administration considerations.
Main Results:
- Reappraisal of synthetic retinoids, phototherapy, and methotrexate.
- Discussion of cyclosporine's availability and administration requirements.
- Overview of therapeutic options for Australian dermatologists.
Conclusions:
- Effective management of severe psoriasis requires a comprehensive understanding of available therapies.
- Dermatologists in Australia have access to a range of treatment options requiring careful selection and administration.