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Updated: Sep 1, 2026

In Vitro Methods for Comparing Target Binding and CDC Induction Between Therapeutic Antibodies: Applications in Biosimilarity Analysis
Published on: May 4, 2017
[Immunotoxicity of drugs]
1Service de Toxicologie clinique Centre Hospitalier Universitaire de Liège.
Abstract:
Immunotoxicity of drugs represents an important problem for 10 to 12% of the overall population. There are 4 types immunotoxicological manifestations of drugs: immediate hypersensitivity, cytotoxic reactions, immune complexes reactions and delayed-type hypersensitivity. The most frequently concerned drugs are penicillins, cephalosporins, anesthetics (type I), erythromycin estolate, nitrofurantoin, sulfonamids, antitubercular agents (type II), quinidine, ticarcillin, valproate, pyramidon (type III) and finally for type IV, topical drugs (antihistaminic products, oestradiol, s.c. heparin).
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