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Updated: Aug 12, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
[Transitional laryngeal papilloma: clinical aspects, diagnosis and treatment]
V F Antoniv1, N A Lusinian, T Ia Vasyliv
1Kafedra otorinolaringologii Rossiĭskogo universiteta druzhby narodov.
Abstract:
Basing on the results of long-term observational study of 200 patients with laryngeal papillomatosis the authors made a conclusion on cycle pattern of the disease course. Each cycle consists of two periods: active (rapid growth of the tumor) and passive (slow growth of the tumor, recurrences are rare, 1-3 years of remission). A case of a male patient is reported illustrating cycle course of transitional laryngeal papilloma. In the beginning of the third cycle, in active period, his papilloma underwent malignant transformation. Cryotherapy of papilloma is thought ineffective.
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